A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it. (Pixabay)

A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it. (Pixabay)

B.C. biotech firm seeks emergency approval for COVID-killing nasal spray

Clinical trials found SaNOtize reduces virus levels in upper airways by more than 99%, developers say

A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it.

The Vancouver start-up said clinical trials found SaNOtize reduced coronavirus levels in participants’ upper airways by 95 per cent in one day and more than 99 per cent in three.

The portable treatment expels a nitric oxide solution, “halt(ing) viral replication within the nasal cavity, which rapidly reduces viral load,” said Dr. Chris Miller, chief science officer and co-founder.

“This is significant because viral load has been linked to infectivity and poor outcomes,” Miller said.

During months of testing, COVID-19 patients in Canada and the U.K. self-administered the nasal spray. When treated quickly enough, the virus was eliminated before it spread to the lungs.

SaNOtize also proved effective against COVID-19 variant B117, which originated in the U.K.

READ MORE: B.C. researchers generating COVID-19 breath test that could give results in 1 minute

None of the participants reported adverse side effects during trials.

If approved for use, SaNOtize could help those with COVID-19 experience milder symptoms and potentially recover quicker from the disease, according to Miller.

“We must move with urgency to get it into the hands of the public where it can help bring an end to the pandemic and prevent future outbreaks of COVID-19 and its variants,” said Dr. Gilly Regev, CEO and co-founder.

The developers are hoping the nasal spray can be used internationally, as a form of protection against COVID-19, similar to that of hand sanitizer.

The biotech company is planning clinical trials to prove SaNOtize can prevent COVID-19 transmission in humans. The product is expected to cost $50 per bottle if it makes its way to consumers.

RELATED: Vancouver biotech company discovering antibodies for COVID-19 treatment



sarah.grochowski@bpdigital.ca

Like us on Facebook and follow us on Twitter.

Want to support local journalism? Make a donation here.

CoronavirusHealth

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

A B.C. Centre for Disease Control map shows new COVID-19 cases by local health area for the week of April 11-17. (BCCDC image)
BCCDC says fresh COVID-19 cases down in most Island Health areas

Nanaimo sees its fewest new COVID-19 cases since mid January

Pharmacist Barbara Violo arranges empty vials of the Oxford-AstraZeneca COVID-19 vaccine that she has provided to customers at the Junction Chemist, an independent pharmacy in Toronto, Monday, April 19, 2021. Younger Canadians in several provinces are now able to get the AstraZeneca vaccine. THE CANADIAN PRESS/Nathan Denette
AstraZeneca vaccine appointments fill up fast on Vancouver Island

More pharmacies expected to be added as supply increases

A 26-foot recreational vehicle was stolen from a Qualicum Beach property early Wednesday morning, April 21. Police found the stolen vehicle nearly three hours later in Whiskey Creek. (Facebook photo)
RCMP act quickly after RV brazenly stolen from Qualicum Beach property

Vehicle recovered, 28-year-old man taken into custody

Canadian Prime Minister Justin Trudeau and United States President Joe Biden smile as they say farewell following a virtual joint statement in Ottawa, Tuesday, February 23, 2021. THE CANADIAN PRESS/Adrian Wyld
Trudeau pledges to cut emissions by 40% to 45% by 2030, short of U.S. goal

Trudeau announced target during a virtual climate summit convened by U.S. President Joe Biden

MLA Shirley Bond, right, answers questions during a press conference at Legislature in Victoria, B.C., on February 19, 2019. THE CANADIAN PRESS/Chad Hipolito
Former B.C. gaming minister says she wasn’t told directly about dirty cash flowing to casinos

Shirley Bond said Thursday civil forfeiture, gang violence and gambling addiction were also major concerns in 2011

RCMP Constable Etsell speaks to tourists leaving the area at a police roadblock on Westside Road south of Fintry, B.C., Thursday, July 23, 2009. THE CANADIAN PRESS/ Yvonne Berg
B.C. police say they take ‘exception’ to conducting roadblocks limiting travel

Asking the police to enforce roadblocks exposes officers to further risk and possible COVID-19 infections, says federation president Brian Sauve

As part of the province’s strategy to combat the opioid overdose crisis, take-home naloxone kits have been distributed throughout the province. (Courtesy of Gaëlle Nicolussi)
Vancouver Island could be at its worst point of overdose crises yet: medical health officer

Island Health issued overdose advisories for Victoria, various communities in the last two weeks

The conservation service confirmed they do not relocate cougars from settled areas but that euthanasia is not necessarily the fate for an animal in the Fanny Bay area. The hope is that the animal will move on to wild areas. (File photo)
Woman hopes cat-stalking Fanny Bay cougar can avoid euthanization

Conservation officers do not relocate the animals from Vancouver Island

Tofino residents expressed frustration over a recent post by Long Beach Lodge owner Tim Hackett that falsely claimed all residents have been vaccinated. (Westerly file photo)
Resort owner apologizes for suggesting Tofino is safe to travel to

Long Beach Lodge owner Tim Hackett apologizes to community and visitors

BC Hydro released a survey Thursday, April 22. It found that many British Columbians are unintentionally contributing to climate change with their yard maintenance choices. (Pixabay)
Spend a lot of time doing yard work? It might be contributing to climate change

Recent BC Hydro survey finds 60% of homeowners still use gas-powered lawnmowers and yard equipment

Journal de Montreal is seen in Montreal, on Thursday, April 22, 2021. The daily newspaper uses a file picture of Prime Minister Justin Trudeau dressed in traditional Indian clothing during his trip to India to illustrate a story on the Indian variant of the coronavirus. Paul Chiasson/The Canadian Press
Montreal newspaper blasted for front-page photo of Trudeau in India

Trudeau is wearing traditional Indian clothes and holding his hands together in prayer beside a caption that reads, ‘The Indian variant has arrived’

Police executed a search warrant at the Devils Army Clubhouse on Petersen road in Campbell River on August 10, 2017.
Murder trial: Victim left to conclude out-of-court settlement on the day he disappeared

Trial of Richard Alexander in death of John Dillon Brown continues in B.C. Supreme Court in Victoria

Most Read